Table 5 Standardised incidence ratios (SIRs) of other cancers

From: Breast cancer risks in women with a family history of breast or ovarian cancer who have tested negative for a BRCA1 or BRCA2 mutation

Cancer type

Observed (rate per 105)

Expected (rate per 105)

SIRs

95% CI

P -value

Breast cancer

65 (713.6)

16.49 (181.0)

3.94

3.09–5.02

<0.0001

Ovarian cancer

2 (21.5)

2.34 (23.3)

0.85

0.23–3.12

0.82

Colon cancer

4 (43.1)

5.04 (48.9)

0.79

0.31–2.04

0.79

All cancers

98 (1083.7)

54.14 (552.5)

1.81

1.49–2.21

<0.0001

All cancers except breast cancer

33 (364.9)

37.78 (385.8)

0.87

0.62–1.23

0.42

  1. Skin cancer is not included as a cancer.
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