Table 2 Correlation analysis of CAIX expression and clinicopathological parameters

From: The key hypoxia regulated gene CAIX is upregulated in basal-like breast tumours and is associated with resistance to chemotherapy

 

CAIX positive ( n =59)

CAIX negative ( n =348)

P -value

Patient age

  

0.96

 Median (years)

55.0

57.0

 

Tumour size

  

0.005

 Median (mm)

25.0

19.0

 

Tumour grade

  

< 0.001

 1

0

96

 

 2

19

189

 

 3

56

154

 

Nodal status

  

0.168

 Negative

34

242

 

 Positive

40

195

 

ER status

  

<0.001

 Negative

54

110

 

 Positive

19

326

 

HER2 status

  

0.065

 Negative

43

291

 

 Positive

16

57

 

Nuclear HIF-1α

  

0.13

 Negative

6

54

 

 Positive

15

62

 
  1. CAIX=carbonic anhydrase IX; PHD=prolyl hydroxylase; HIF=hypoxia-inducible factor.
  2. n<456 because data are not available.
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