Table 1 Gene ontology

From: Overexpressed vs mutated Kras in murine fibroblasts: a molecular phenotyping study

GO term

Gene symbol

(A) Molecular functions

 

Calcium–ion binding

Anxa2, Anxa3, Anxa5, Fbln2, S100A11, S100A6, Sparc, Ssr4

Nucleic acid binding

Nfic, RPl18, Runx3, Sfrs3, Snrpf, Zfp36l1

Catalytic activity

Anxa3, Atp5a1, Cox7b, Lox, Rac1, Sod1

Transporter activity

Atp5a1, Atp5 l, Cox7b, Fabp5, Sec61G

Structural molecule activity

Col1a1, Fbln2, Rpl13a, Rpl18, Vim

Enzyme regulator activity

Anxa2, Anxa3, anxa5, S100a6

Lipid binding

Anxa2, Anxa3, Anxa5, Fabp5

Oxidoreductase activity

Cox7b, Lox, Sod1

Protein binding

S100A6, Sparc, Vim

(B) Biological processes

 

Cell growth

Atp5a1, Atp5 l, Fabp5, Nfic, Rac1, Runx3, S100a11, S100a6, Sec61 g, Ssr4, Zfp36l1

Development

Anxa2, Col1a1, Cox7b, Fabp5, Rac1, S100a6, Sod1, Sparc

Nucleic acid metabolism

Atp5a1, Atp5 l, Nfic, Runx3, S100a11, Sfrs3, Snrpf

Cell proliferation

Nfic, Ras1, Runx3, S100a11, S100a6, Zfp36l1

Protein metabolism

Lox, Rpl13a, Rpl18, Sec61g