Table 3 Univariate analysis of survival

From: RASSF1A hypermethylation in pretreatment serum DNA of neuroblastoma patients: a prognostic marker

Characteristic

Hazard ratio

95% CI

P -value

Age at diagnosis

 <12 months

Reference

  

12 months

23.6

3.1–181.9

0.002

Sex

 Male

Reference

  

 Female

1.0

0.3–3.0

0.983

Stage

 1/2/3/4S

Reference

  

 4

19.8

4.4–89.5

<0.001

MYCN

 Non-amplified

Reference

  

 Amplified

8.2

2.7–24.7

<0.001

Serum RASSF1A

 Unmethylated

Reference

  

 Methylated

9.2

2.8–30.1

<0.001

  1. CI=confidence interval.