Table 1 SIR for subsequent cancer in patients with hospitalised asthma during the follow-up time
Follow-up interval (years) | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
<1 | 1–4 | 5–9 | ⩾10 | All | All 1+ | |||||||||||||
Cancer site | O | SIR | 95% CI | O | SIR | 95% CI | O | SIR | 95% CI | O | SIR | 95% CI | O | SIR | 95% CI | O | SIR | 95% CI |
Upper aerodigestive tract | 20 | 1.77 | (1.08, 2.73) | 37 | 1.11 | (0.78, 1.53) | 36 | 1.26 | (0.88, 1.74) | 42 | 1.09 | (0.79, 1.48) | 135 | 1.21 | (1.01, 1.43) | 115 | 1.14 | (0.94, 1.37) |
Oesophagus | 9 | 1.99 | (0.90, 3.79) | 29 | 2.14 | (1.43, 3.08) | 28 | 2.39 | (1.59, 3.46) | 19 | 1.20 | (0.72, 1.88) | 85 | 1.87 | (1.49, 2.31) | 76 | 1.85 | (1.46, 2.32) |
Stomach | 49 | 2.41 | (1.78, 3.18) | 98 | 1.72 | (1.40, 2.10) | 44 | 0.96 | (0.70, 1.30) | 68 | 1.20 | (0.94, 1.53) | 259 | 1.44 | (1.27, 1.63) | 210 | 1.32 | (1.15, 1.51) |
Colon | 98 | 2.34 | (1.90, 2.85) | 225 | 1.77 | (1.55, 2.02) | 170 | 1.54 | (1.32, 1.79) | 210 | 1.42 | (1.24, 1.63) | 703 | 1.65 | (1.53, 1.77) | 605 | 1.57 | (1.45, 1.70) |
Rectum | 49 | 2.12 | (1.57, 2.81) | 82 | 1.18 | (0.94, 1.47) | 72 | 1.20 | (0.94, 1.51) | 108 | 1.33 | (1.09, 1.61) | 311 | 1.33 | (1.19, 1.49) | 262 | 1.24 | (1.10, 1.40) |
Liver | 48 | 2.94 | (2.17, 3.90) | 89 | 1.88 | (1.51, 2.31) | 59 | 1.51 | (1.15, 1.95) | 49 | 0.99 | (0.73, 1.31) | 245 | 1.61 | (1.41, 1.82) | 197 | 1.45 | (1.25, 1.67) |
Pancreas | 44 | 2.90 | (2.10, 3.89) | 58 | 1.31 | (1.00, 1.70) | 55 | 1.50 | (1.13, 1.95) | 66 | 1.40 | (1.08, 1.78) | 223 | 1.56 | (1.36, 1.78) | 179 | 1.40 | (1.20, 1.62) |
Lung | 285 | 6.98 | (6.19, 7.84) | 294 | 2.41 | (2.14, 2.70) | 186 | 1.76 | (1.52, 2.04) | 170 | 1.20 | (1.03, 1.40) | 935 | 2.28 | (2.14, 2.43) | 650 | 1.76 | (1.63, 1.90) |
Breast | 71 | 1.09 | (0.85, 1.38) | 221 | 1.05 | (0.91, 1.20) | 172 | 0.89 | (0.76, 1.04) | 297 | 1.07 | (0.95, 1.20) | 761 | 1.02 | (0.95, 1.09) | 690 | 1.01 | (0.94, 1.09) |
Cervix | 11 | 1.79 | (0.89, 3.21) | 30 | 1.56 | (1.05, 2.23) | 20 | 1.18 | (0.72, 1.83) | 32 | 1.28 | (0.87, 1.81) | 93 | 1.38 | (1.11, 1.69) | 82 | 1.34 | (1.07, 1.66) |
Endometrium | 18 | 1.18 | (0.70, 1.87) | 36 | 0.74 | (0.52, 1.02) | 30 | 0.68 | (0.46, 0.98) | 45 | 0.76 | (0.55, 1.01) | 129 | 0.77 | (0.64, 0.92) | 111 | 0.73 | (0.60, 0.88) |
Ovary | 19 | 1.60 | (0.96, 2.50) | 38 | 1.02 | (0.72, 1.40) | 29 | 0.89 | (0.60, 1.28) | 38 | 0.87 | (0.61, 1.19) | 124 | 0.99 | (0.82, 1.18) | 105 | 0.92 | (0.76, 1.12) |
Prostate | 178 | 2.12 | (1.82, 2.45) | 346 | 1.38 | (1.24, 1.53) | 265 | 1.19 | (1.05, 1.35) | 397 | 1.26 | (1.14, 1.39) | 1186 | 1.36 | (1.29, 1.44) | 1008 | 1.28 | (1.20, 1.36) |
Kidney | 38 | 2.40 | (1.70, 3.30) | 71 | 1.55 | (1.21, 1.95) | 60 | 1.61 | (1.23, 2.07) | 38 | 0.79 | (0.56, 1.08) | 207 | 1.41 | (1.22, 1.61) | 169 | 1.29 | (1.10, 1.50) |
Urinary bladder | 59 | 2.21 | (1.68, 2.85) | 117 | 1.47 | (1.21, 1.76) | 87 | 1.26 | (1.01, 1.56) | 113 | 1.21 | (1.00, 1.45) | 376 | 1.40 | (1.26, 1.55) | 317 | 1.31 | (1.17, 1.46) |
Melanoma | 15 | 1.02 | (0.57, 1.69) | 30 | 0.63 | (0.43, 0.90) | 42 | 0.93 | (0.67, 1.26) | 65 | 0.89 | (0.68, 1.13) | 152 | 0.84 | (0.71, 0.99) | 137 | 0.83 | (0.69, 0.98) |
Skin, squamous cell | 36 | 1.56 | (1.09, 2.16) | 92 | 1.28 | (1.03, 1.57) | 83 | 1.30 | (1.04, 1.61) | 116 | 1.32 | (1.09, 1.59) | 327 | 1.33 | (1.19, 1.48) | 291 | 1.30 | (1.16, 1.46) |
Nervous system | 48 | 3.01 | (2.22, 3.99) | 57 | 1.13 | (0.86, 1.47) | 51 | 1.15 | (0.85, 1.51) | 66 | 1.08 | (0.84, 1.38) | 222 | 1.29 | (1.13, 1.48) | 174 | 1.12 | (0.96, 1.30) |
Endocrine glands | 28 | 3.11 | (2.07, 4.51) | 33 | 1.18 | (0.81, 1.67) | 29 | 1.19 | (0.79, 1.70) | 37 | 1.07 | (0.75, 1.47) | 127 | 1.32 | (1.10, 1.57 | 99 | 1.14 | (0.92, 1.39) |
Non-Hodgkin's lymphoma | 42 | 1.87 | (1.35, 2.53) | 54 | 0.78 | (0.58, 1.02) | 47 | 0.77 | (0.56, 1.02) | 87 | 1.03 | (0.82, 1.27) | 230 | 0.97 | (0.85, 1.10) | 188 | 0.87 | (0.75, 1.01) |
Myeloma | 13 | 1.65 | (0.87, 2.82) | 24 | 1.02 | (0.65, 1.52) | 21 | 1.05 | (0.65, 1.60) | 31 | 1.16 | (0.79, 1.65) | 89 | 1.14 | (0.91, 1.40) | 76 | 1.08 | (0.85, 1.35) |
Leukaemia | 40 | 3.25 | (2.32, 4.42) | 56 | 1.51 | (1.14, 1.96) | 47 | 1.56 | (1.15, 2.08) | 45 | 1.24 | (0.90, 1.65) | 188 | 1.62 | (1.40, 1.87) | 148 | 1.43 | (1.21, 1.68) |
All | 1264 | 2.40 | (2.27, 2.54) | 2205 | 1.38 | (1.32, 1.44) | 1700 | 1.21 | (1.15, 1.27) | 2252 | 1.16 | (1.11, 1.21) | 7421 | 1.36 | (1.33, 1.39) | 6157 | 1.24 | (1.21, 1.28) |