Table 2 SIR for subsequent cancer in patients hospitalised for asthma by number of hospitalisations
Number of hospitalisations | |||||||||
|---|---|---|---|---|---|---|---|---|---|
1 | 2–5 | ⩾6 | |||||||
Cancer site | O | SIR | 95% CI | O | SIR | 95% CI | O | SIR | 95% CI |
Upper aerodigestive tract | 65 | 1.15 | (0.89, 1.47) | 43 | 1.31 | (0.95, 1.76) | 7 | 0.62 | (0.24, 1.28) |
Oesophagus | 39 | 1.72 | (1.22, 2.36) | 30 | 2.21 | (1.49, 3.16) | 7 | 1.45 | (0.57, 3.00) |
Stomach* | 98 | 1.11 | (0.90, 1.35) | 81 | 1.54 | (1.22, 1.92) | 31 | 1.70 | (1.15, 2.41) |
Colon** | 302 | 1.43 | (1.27, 1.60) | 212 | 1.66 | (1.44, 1.90) | 91 | 1.99 | (1.60, 2.44) |
Rectum | 149 | 1.28 | (1.08, 1.51) | 78 | 1.12 | (0.88, 1.40) | 35 | 1.42 | (0.99, 1.98) |
Liver | 110 | 1.47 | (1.21, 1.77) | 61 | 1.35 | (1.03, 1.73) | 26 | 1.62 | (1.06, 2.38) |
Pancreas | 97 | 1.37 | (1.11, 1.67) | 59 | 1.39 | (1.06, 1.80) | 23 | 1.55 | (0.98, 2.33) |
Lung** | 402 | 1.96 | (1.78, 2.16) | 190 | 1.56 | (1.35, 1.80) | 58 | 1.36 | (1.04, 1.76) |
Breast | 399 | 1.04 | (0.94, 1.14) | 217 | 0.98 | (0.85, 1.12) | 74 | 0.99 | (0.78, 1.24) |
Cervix | 46 | 1.30 | (0.95, 1.73) | 28 | 1.43 | (0.95, 2.07) | 8 | 1.29 | (0.55, 2.55) |
Endometrium | 67 | 0.79 | (0.62, 1.01) | 36 | 0.71 | (0.50, 0.99) | 8 | 0.46 | (0.19, 0.90) |
Ovary | 60 | 0.93 | (0.71, 1.20) | 34 | 0.92 | (0.63, 1.28) | 11 | 0.90 | (0.44, 1.61) |
Prostate | 525 | 1.21 | (1.11, 1.32) | 359 | 1.37 | (1.24, 1.52) | 124 | 1.33 | (1.10, 1.58) |
Kidney | 94 | 1.27 | (1.03, 1.56) | 52 | 1.21 | (0.90, 1.59) | 23 | 1.59 | (1.00, 2.38) |
Urinary bladder | 189 | 1.42 | (1.22, 1.63) | 97 | 1.21 | (0.98, 1.48) | 31 | 1.09 | (0.74, 1.55) |
Melanoma | 72 | 0.76 | (0.59, 0.95) | 48 | 0.90 | (0.66, 1.19) | 17 | 0.97 | (0.57, 1.56) |
Skin, squamous cell | 151 | 1.25 | (1.06, 1.47) | 94 | 1.26 | (1.02, 1.54) | 46 | 1.64 | (1.20, 2.19) |
Nervous system | 93 | 1.01 | (0.81, 1.23) | 58 | 1.19 | (0.91, 1.54) | 23 | 1.58 | (1.00, 2.38) |
Endocrine glands | 70 | 1.42 | (1.11, 1.79) | 23 | 0.81 | (0.51, 1.22) | 6 | 0.64 | (0.23, 1.40) |
Non-Hodgkin's lymphoma | 90 | 0.75 | (0.60, 0.92) | 71 | 0.01 | (0.79, 1.27) | 27 | 1.11 | (0.73, 1.62) |
Myeloma | 42 | 1.08 | (0.78, 1.47) | 24 | 1.03 | (0.66, 1.54) | 10 | 1.21 | (0.58, 2.24) |
Leukaemia | 89 | 1.46 | (1.17, 1.80) | 47 | 1.45 | (1.07, 1.93) | 12 | 1.18 | (0.61, 2.07) |
All | 3407 | 1.23 | (1.19, 1.27) | 2028 | 1.25 | (1.20, 1.30) | 722 | 1.29 | (1.20, 1.38) |
