Table 3 SIR for subsequent cancer in patients with hospitalised asthma during diagnosis period

From: Cancer risk in hospitalised asthma patients

 

1970s

1980s

1990s

Cancer site

O

SIR

95% CI

O

SIR

95% CI

O

SIR

95% CI

Upper aerodigestive tract

12

0.92

(0.47, 1.62)

44

1.17

(0.85, 1.57)

35

1.27

(0.88, 1.77)

Oesophagus

12

2.73

(1.40, 4.78)

18

1.18

(0.70, 1.87)

34

2.79

(1.93, 3.91)

Stomach**

22

0.92

(0.58, 1.39)

81

1.36

(1.08, 1.69)

71

1.67

(1.30, 2.10)

Colon

63

1.69

(1.30, 2.17)

216

1.54

(1.34, 1.75)

201

1.67

(1.45, 1.92)

Rectum

32

1.51

(1.03, 2.14)

81

1.04

(0.83, 1.30)

83

1.29

(1.03, 1.60)

Liver

33

1.98

(1.36, 2.78)

87

1.70

(1.36, 2.10)

54

1.35

(1.01, 1.76)

Pancreas

18

1.11

(0.66, 1.76)

79

1.66

(1.32, 2.08)

49

1.32

(0.97, 1.74)

Lung

96

2.31

(1.87, 2.83)

215

1.58

(1.38, 1.81)

238

2.21

(1.94, 2.51)

Breast

63

1.09

(0.84, 1.40)

239

1.01

(0.88, 1.14)

205

0.93

(0.81, 1.07)

Cervix

14

1.68

(0.92, 2.83)

29

1.39

(0.93, 2.00)

20

1.22

(0.74, 1.89)

Endometrium

8

0.64

(0.27, 1.27)

41

0.77

(0.55, 1.05)

41

0.79

(0.56, 1.07)

Ovary

16

1.23

(0.70, 2.01)

38

0.94

(0.67, 1.29)

28

0.81

(0.54, 1.17)

Prostate

97

1.38

(1.12, 1.68)

362

1.22

(1.10, 1.35)

303

1.28

(1.14, 1.43)

Kidney

17

1.00

(0.58, 1.61)

70

1.46

(1.14, 1.84)

61

1.61

(1.23, 2.07)

Urinary bladder

41

1.63

(1.17, 2.21)

115

1.27

(1.04, 1.52)

92

1.29

(1.04, 1.58)

Melanoma*

6

0.39

(0.14, 0.85)

45

0.77

(0.56, 1.03)

45

0.95

(0.69, 1.27)

Skin, squamous cell

18

1.13

(0.67, 1.78)

104

1.25

(1.02, 1.51)

96

1.32

(1.07, 1.61)

Nervous system

23

1.30

(0.82, 1.95)

75

1.41

(1.11, 1.76)

40

0.83

(0.59, 1.13)

Endocrine glands

14

1.49

(0.81, 2.50)

41

1.32

(0.95, 1.80)

28

1.09

(0.72, 1.58)

Non-Hodgkin's lymphoma**

21

1.39

(0.86, 2.13)

76

1.26

(0.99, 1.58)

45

0.85

(0.62, 1.14)

Myeloma

4

0.53

(0.14, 1.38)

31

1.19

(0.81, 1.69)

22

1.03

(0.65, 1.57)

Leukaemia

16

1.00

(0.57, 1.64)

50

0.94

(0.70, 1.24)

56

1.11

(0.84, 1.44)

All

675

1.35

(1.25, 1.45)

2213

1.23

(1.18, 1.28)

1932

1.29

(1.23, 1.34)

  1. CI=confidence interval; SIR=standardised incidence ratio.
  2. Bold values represent 95% CI that does not include 1.00. Underline values represent 99% CI that does not include 1.00. *P-value for trend is <0.05. **P-value for trend is <0.01.
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