Table 1 Relative risks for adenocarcinomas of the oesophagus (OAC), gastro-oesophageal junction (GOJAC) and squamous cell carcinoma (OSCC) associated with type 2 diabetes; minimally, partially and fully adjusted for confounding factors
From: Does type 2 diabetes influence the risk of oesophageal adenocarcinoma?
History of type 2 diabetes | Control ( N) | Case ( N) | OR (95% CI) a | OR (95% CI) b | OR (95% CI) c |
|---|---|---|---|---|---|
OAC | |||||
No diabetes | 1423 | 293 | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) |
Diabetes | 103 | 46 | 1.78 (1.22–2.62) | 1.59 (1.04–2.43) | 1.32 (0.85–2.05) |
No diabetes | 1423 | 293 | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) |
Diabetes duration <10 years | 68 | 25 | 1.46 (0.90–2.38) | 1.39 (0.82–2.36) | 1.14 (0.66–1.97) |
Diabetes duration ⩾10 years) | 30 | 18 | 2.45 (1.32–4.57) | 1.96 (0.97–3.97) | 1.65 (0.80–3.40) |
P-trend | 0.18 | ||||
GOJAC | |||||
No diabetes | 1423 | 338 | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) |
Diabetes | 103 | 44 | 1.56 (1.06–2.28) | 1.44 (0.96–2.16) | 1.23 (0.82–1.87) |
No diabetes | 1423 | 338 | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) |
Diabetes (duration <10 years) | 68 | 20 | 1.06 (0.63–1.79) | 0.90 (0.57–1.71) | 0.87 (0.50–1.51) |
Diabetes (duration ⩾10 years) | 30 | 22 | 2.76 (1.55–4.91) | 2.46 (1.33–4.55) | 2.16 (1.16–4.04) |
P-trend | 0.07 | ||||
OSCC | |||||
No diabetes | 1423 | 270 | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) |
Diabetes | 103 | 12 | 0.54 (0.29–1.0) | 0.48 (0.25–0.91) | 0.57 (0.30–1.10) |
No diabetes | 1423 | 270 | 1.0 (ref) | 1.0 (ref) | 1.0 (ref) |
Diabetes (duration <10 years) | 68 | 7 | 0.49 (0.22–1.08) | 0.42 (0.18–0.97) | 0.52 (0.23–1.20) |
Diabetes (duration ⩾10 years) | 30 | 5 | 0.73 (0.28–1.92) | 0.62 (0.23–1.67) | 0.70 (0.25–1.93) |
P-trend | 0.17 | ||||
