Table 3 Joint effect of WC status and plasma leptin levels on breast cancer risk
From: Circulating levels of leptin, adiposity and breast cancer risk
Group | WC a (cm) | Leptina (ng ml−1) | No. of cases (%) | No. of controls (%) | OR b (95% CI) | P trend |
|---|---|---|---|---|---|---|
All women | ||||||
⩽80 | ⩽10.9 | 153 (51.9) | 375 (63.8) | 1.00 (reference) | ||
⩽80 | >10.9 | 45 (15.2) | 65 (11.0) | 2.00 (1.27–3.17) | ||
>80 | ⩽10.9 | 38 (12.9) | 71 (12.1) | 1.65 (0.99–2.76) | ||
>80 | >10.9 | 59 (20.0) | 77 (13.1) | 2.51 (1.51–4.19) | 0.0006 | |
Premenopausal | ||||||
⩽80 | ⩽10.6 | 110 (64.0) | 214 (64.5) | 1.00 (reference) | ||
⩽80 | >10.6 | 25 (14.5) | 35 (10.5) | 1.90 (0.98–4.02) | ||
>80 | ⩽10.6 | 10 (5.8) | 37 (11.1) | 1.29 (0.59–2.83) | ||
>80 | >10.6 | 27 (15.7) | 46 (13.9) | 1.99 (1.06–3.39) | 0.0572 | |
Postmenopausal | ||||||
⩽80 | ⩽11.5 | 47 (38.2) | 149 (58.0) | 1.00 (reference) | ||
⩽80 | >11.5 | 15 (12.2) | 30 (11.7) | 1.64 (0.77–3.53) | ||
>80 | ⩽11.5 | 27 (22.0) | 46 (17.9) | 1.85 (0.91–3.75) | ||
>80 | >11.5 | 34 (27.6) | 32 (12.4) | 3.25 (1.53–6.91) | 0.0029 |
