Figure 5

Kaplan–Meier curves showing association between cell-cycle phenotype and disease-free survival. (I) Out-of-cycle state, (II) in cycle G1-delayed/arrested state and (III) actively cycling state. On univariate analysis, comparing phenotype III with phenotypes I and II combined, HR=3.90 (1.81–8.40), P<0.001. On multivariate analysis, adjusted for NPI, HR=2.71 (1.18–6.23), P=0.019.