Table 1 MicroRNAs significantly altered in NPC tissues
From: MicroRNA deregulation and pathway alterations in nasopharyngeal carcinoma
Mean expression a | P -value | |||||
|---|---|---|---|---|---|---|
MicroRNA | Chromosome | Normal | NPC | Fold change | T -test | Mann–Whitney |
U-regulated | ||||||
miR-196b | 7p15 | 4.04 | 6.75 | 6.54 | 1.45E−04 | 2.68E−03 |
miR-138 | 3p21, 16q13 | 4.58 | 7.27 | 6.45 | 7.77E−04 | 4.04E−03 |
miR-155 | 21q21 | 7.50 | 10.09 | 6.04 | 2.05E−05 | 1.75E−03 |
miR-142-3p | 17q22 | 9.43 | 11.73 | 4.92 | 6.95E−04 | 1.75E−03 |
miR-18a | 13q31 | 5.20 | 7.50 | 4.92 | 6.00E−05 | 1.75E−03 |
miR-25a | 7q22 | 7.22 | 9.28 | 4.18 | 3.43E−05 | 1.75E−03 |
miR-205 | 1q32 | 16.01 | 18.02 | 4.00 | 1.51E−03 | 4.04E−03 |
miR-106a | Xq26 | 9.25 | 11.18 | 3.80 | 2.37E−04 | 4.04E−03 |
miR-17 | 13q31 | 10.67 | 12.41 | 3.34 | 2.08E−03 | 8.81E−03 |
miR-15ba | 3q26 | 4.68 | 6.39 | 3.27 | 2.38E−04 | 1.75E−03 |
miR-17a | 13q31 | 5.15 | 6.84 | 3.22 | 4.40E−04 | 1.75E−03 |
Downregulated | ||||||
miR-204 | 9q21 | 10.37 | 4.91 | −44.15 | 3.51E−07 | 1.75E−03 |
miR-449a | 5q11 | 8.54 | 4.42 | −17.45 | 4.28E−05 | 2.68E−03 |
miR-34c-3p | 11q23 | 11.92 | 8.15 | −13.64 | 1.55E−03 | 6.01E−03 |
miR-187 | 18q12 | 10.23 | 6.80 | −10.74 | 1.26E−04 | 1.75E−03 |
miR-145 | 5q33 | 16.77 | 13.39 | −10.42 | 7.03E−05 | 1.75E−03 |
miR-143 | 5q33 | 12.50 | 9.17 | −10.07 | 2.89E−05 | 1.75E−03 |
miR-34c-5p | 11q23 | 9.30 | 6.04 | −9.63 | 2.49E−03 | 8.81E−03 |
miR-34b | 11q23 | 8.36 | 5.37 | −7.92 | 5.74E−03 | 8.81E−03 |
miR-100 | 11q24 | 12.93 | 10.05 | −7.36 | 6.79E−04 | 1.75E−03 |
miR-9 | 1q22, 5q14, 15q26 | 7.16 | 4.34 | −7.07 | 7.34E−05 | 1.75E−03 |
miR-139-5p | 11q13 | 11.59 | 8.83 | −6.75 | 1.18E−06 | 1.75E−03 |
miR-195 | 17p13 | 9.98 | 7.26 | −6.61 | 9.96E−05 | 1.75E−03 |
miR-148a | 7p15 | 8.13 | 5.46 | −6.36 | 2.33E−04 | 2.68E−03 |
miR-30aa | 6q13 | 10.08 | 7.50 | −5.99 | 2.10E−03 | 8.81E−03 |
miR-497 | 17p13 | 12.12 | 9.63 | −5.62 | 1.64E−04 | 2.68E−03 |
miR-135a | 3p21, 12q23 | 7.88 | 5.71 | −4.49 | 3.63E−03 | 4.04E−03 |
miR-130a | 11q12 | 9.94 | 7.84 | −4.29 | 2.77E−04 | 2.68E−03 |
miR-31 | 9p21 | 12.53 | 10.51 | −4.05 | 1.50E−03 | 6.01E−03 |
miR-199b-5p | 9q34 | 7.67 | 5.74 | −3.83 | 2.05E−03 | 6.01E−03 |
miR-200a | 1p36 | 7.32 | 5.59 | −3.32 | 1.87E−03 | 4.04E−03 |
miR-29c | 1q32 | 7.78 | 6.09 | −3.25 | 2.53E−03 | 1.27E−02 |
miR-152 | 17q21 | 10.30 | 8.65 | −3.13 | 1.04E−03 | 6.01E−03 |
miR-200b | 1p36 | 12.01 | 10.36 | −3.13 | 1.59E−03 | 1.75E−03 |
miR-532-3p | Xp11 | 13.52 | 11.92 | −3.03 | 4.10E−03 | 8.81E−03 |
