Table 3 Cutoff scores of the HADS subscales and total score

From: Hospital anxiety and depression scale cutoff scores for cancer patients in acute care

 

Score

Sensitivity

Specificity

(Sensitivity+specificity)/2

PPV

NPV

HADS Depression

 Clinical

⩾2

0.95

0.21

0.58

0.35

0.89

 Regular ZS

⩾8

0.55

0.75

0.65

0.50

0.78

 Balanced

⩾5

0.82

0.49

0.65

0.42

0.85

 Specific ZS

⩾11

0.30

0.88

0.59

0.53

0.73

 Specific

⩾15

0.10

0.96

0.53

0.51

0.70

HADS anxiety

 Clinical

⩾3

0.95

0.18

0.56

0.35

0.88

 Regular ZS

⩾8

0.67

0.67

0.66

0.48

0.82

 Balanced

⩾7

0.75

0.56

0.67

0.44

0.83

 Specific ZS

⩾11

0.37

0.86

0.62

0.55

0.75

 Specific

⩾15

0.11

0.95

0.53

0.53

0.70

HADS total score

 Clinical

⩾6

0.96

0.21

0.59

0.36

0.91

 Regular ZS

⩾16

0.59

0.76

0.67

0.53

0.80

 Balanced

⩾13

0.76

0.60

0.68

0.47

0.84

 Specific ZS

⩾22

0.30

0.89

0.59

0.54

0.73

 Specific

⩾27

0.14

0.95

0.55

0.57

0.71

  1. Balanced=best trade between sensitivity and specificity; Clinical=recommended score for clinical purposes, that is, sensitivity min 0.95; Regular ZS=optimal score in identifying suspicious cases according to Zigmond and Snaith; Specific=specificity min 0.95; Specific ZS=optimal score in identifying safe cases according to Zigmond and Snaith; NPV=negative predictive value; PPV=positive predictive value.
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