Table 3 Univariate and multivariate analyses of prognostic factors on the PFS of 139 ovarian epithelial carcinoma patients

From: High mesothelin correlates with chemoresistance and poor survival in epithelial ovarian carcinoma

 

Univariate

Multivariate

 

Odds ratio (95% CI)

P -value a

Odds ratio (95% CI)

P -value a

Histology

 Serous/non-serous

1.46 (0.91–2.35)

0.12

  

Stage

 III and IV/I and II

1.84 (1.32–2.57)

<0.001

1.38 (0.95–2.02)

0.094b

Grade

 3/1 and 2

1.21 (0.95–1.54)

0.12

  

Optimal debulking surgery

 No/yes

2.36 (1.50–3.70)

<0.001

1.37 (0.82–2.29)

0.23b

Lymph node metastasis

 Yes/no

1.56 (0.83–2.92)

0.17

  

CA125 levels>/1000 U ml−1

1.34 (0.86–2.09)

0.21

  

Time to normal CA125 level

 Longer/less than 63 days

3.45 (2.17–5.47)

<0.001

2.14 (1.28–3.58)

0.004b

Mesothelin expression level

 Highly vs low

2.63 (1.62–4.26)

<0.001

2.03 (1.23–3.37)

0.006b

  1. Abbreviations: CI=confidence interval; PFS=progression-free survival.
  2. aBy Kaplan–Meier test.
  3. bVariable included in the multivariate model.