Table 3 Univariate and multivariate analyses of prognostic factors on the PFS of 139 ovarian epithelial carcinoma patients
From: High mesothelin correlates with chemoresistance and poor survival in epithelial ovarian carcinoma
Univariate | Multivariate | |||
---|---|---|---|---|
Odds ratio (95% CI) | P -value a | Odds ratio (95% CI) | P -value a | |
Histology | ||||
Serous/non-serous | 1.46 (0.91–2.35) | 0.12 | ||
Stage | ||||
III and IV/I and II | 1.84 (1.32–2.57) | <0.001 | 1.38 (0.95–2.02) | 0.094b |
Grade | ||||
3/1 and 2 | 1.21 (0.95–1.54) | 0.12 | ||
Optimal debulking surgery | ||||
No/yes | 2.36 (1.50–3.70) | <0.001 | 1.37 (0.82–2.29) | 0.23b |
Lymph node metastasis | ||||
Yes/no | 1.56 (0.83–2.92) | 0.17 | ||
CA125 levels>/⩽1000 U ml−1 | 1.34 (0.86–2.09) | 0.21 | ||
Time to normal CA125 level | ||||
Longer/less than 63 days | 3.45 (2.17–5.47) | <0.001 | 2.14 (1.28–3.58) | 0.004b |
Mesothelin expression level | ||||
Highly vs low | 2.63 (1.62–4.26) | <0.001 | 2.03 (1.23–3.37) | 0.006b |