Table 4 Univariate and multivariate analyses of prognostic factors on the overall survival of 139 ovarian epithelial carcinoma patients
From: High mesothelin correlates with chemoresistance and poor survival in epithelial ovarian carcinoma
Odds ratio (95% CI) | P -value a | Odds ratio (95% CI) | P -value a | |
|---|---|---|---|---|
Histology | ||||
Serous/non-serous | 1.25 (0.64–2.44) | 0.51 | ||
Stage | ||||
III and IV/I and II | 2.08 (1.24–3.50) | 0.006 | 1.55 (0.86–2.82) | 0.15b |
Grade | ||||
3/1 and 2 | 1.04 (0.75–1.42) | 0.83 | ||
Optimal debulking surgery | ||||
No/yes | 3.35 (1.71–6.54) | <0.001 | 1.88 (0.84–4.17) | 0.12b |
Lymph node metastasis | ||||
Yes/no | 1.67 (0.62–4.49) | 0.31 | ||
CA125 levels >1000 U ml−1 | 1.88 (0.97–3.63) | 0.06 | ||
Time to normal CA125 level | ||||
Longer/less than 63 days | 3.41 (1.80–6.47) | <0.001 | 1.93 (0.88–4.22) | 0.099b |
Mesothelin expression level | ||||
High vs low | 4.64 (2.15–10.03) | <0.001 | 3.72 (1.64–8.45) | 0.002b |
