Table 1 Correlation of WWOX expression with clinicopathological findings in IPMA

From: Hypermethylation-mediated reduction of WWOX expression in intraductal papillary mucinous neoplasms of the pancreas

 

WWOX(−)

WWOX(+)

 

IPMA

(n =3)

(n =17)

P -value a

Age (years)

 Average

71.0±2.6

69.9±7.9

0.816

Gender

   

 Male

2%

13%

0.860

 Female

1%

4%

 

Tumour size (mm)

 Average

20.7±12.5

41.0±20.7

0.121

Main duct (mm)

 Average

12.3±3.1

5.6±3.4

0.006

Location

   

 Head

3%

12%

0.399

 Body/Tail

0%

5%

 

Tumour type

   

 Main duct

2%

6%

0.344

 Branch

1%

11%

 

Ki-67 LIb

22.3±6.5

5.1±5.1

<0.001

ssDNA ABIb

1.7±0.8

1.4±0.9

0.624

  1. IPMA=intraductal papillary mucinous adenoma; Ki-67 LI=Ki-67 labelling index; ssDNA ABI=ssDNA apoptotic body index.
  2. aP-value less than 0.05 was considered to be statistically significant.
  3. b Ki-67 LI was determined by counting the positive cells in 1000 tumour cells, whereas the ssDNA ABI was determined by counting the ssDNA-positive cells in 10 high-power fields.
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