Table 2 Correlation of WWOX expression with clinicopathological findings in IPMC

From: Hypermethylation-mediated reduction of WWOX expression in intraductal papillary mucinous neoplasms of the pancreas

 

WWOX(−)

WWOX(+)

 

IPMC

(n =17)

(n =4)

P -value a

Age (years)

 Average

68.7±7.6

57.8±9.1

0.022

Gender

   

 Male

7%

1%

0.502

 Female

10%

3%

 

Tumour size (mm)

 Average

61.9±32.9

50.0±24.5

0.507

Main duct (mm)

 Average

9.5±3.8

5.8±1.7

0.071

Location

   

 Head

12%

3%

0.684

 Body/Tail

5%

1%

 

Tumour type

   

 Main duct

14%

3%

0.852

 Branch

3%

1%

 

Ki-67 LIb

27.6±10.8

14.4±3.3

0.109

ssDNA ABIb

1.5±1.2

1.2±0.4

0.767

  1. IPMC=intraductal papillary mucinous carcinoma; Ki-67 LI=Ki-67 labelling index; ssDNA ABI=ssDNA apoptotic body index.
  2. aP-value less than 0.05 was considered to be statistically significant.
  3. b Ki-67 LI was determined by counting the positive cells in 1000 tumour cells, whereas the ssDNA ABI was determined by counting the ssDNA-positive cells in 10 high-power fields.
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