Figure 7

Western blots of tumour lysates obtained 2 h after the final dose of NVP-BEZ235 in the chronic dosing groups of animals, probed for Ser473 Akt and Ser235/236 and Ser240/244 S6 ribosomal protein, with actin loading controls. Owing to their small size, insufficient material was available for the OCIP19 tumours.