Table 3 Tumour marker accuracy and sensitivity at 95% specificity for ovarian cancer and ovarian endometriosis
From: Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts
Markers | Accuracy (%) | ROC-AUC (%) | Sensitivity (%) |
|---|---|---|---|
OvCa vs OvEndo | |||
CA125+HE4 | 94.0 | 91.3 | 78.6 |
CA125 | 92.8 | 77.0 | 64.3 |
HE4 | 91.6 | 91.9 | 71.4 |
OvCa vs ctrl | |||
CA125+HE4 | 96.3 | 91.1 | 92.9 |
CA125 | 96.3 | 91.7 | 78.6 |
HE4 | 93.8 | 95.5 | 78.6 |
OvEndo vs ctrl | |||
CA125+HE4 | 82.2 | 86.8 | 62.3 |
CA125 | 83.0 | 87.7 | 60.9 |
HE4 | 60.7 | 60.5 | 5.8 |
OvCa vs OvEndo vs ctrl | |||
CA125+HE4 | 81.9 | ||
CA125 | 81.2 | ||
HE4 | 59.7 | ||
