Table 4 Expression of WFDC2 (HE4) and MUC16 (CA125) mRNA in tissue specimens of endometrium, non-ovarian and ovarian endometriosis, endometrial cancer, and ovarian cancer as log2 intensity values

From: Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts

  

WFDC2

MUC16

Sample group

N

Median

25%

75%

FC

P -value a

Median

25%

75%

FC

P -value a

E of healthy control

41

7.67

6.96

8.28

  

7.1

6.76

7.48

  

E of endo patient

64

7.75

7.17

8.28

1.1b

NSb

7.21

6.86

7.63

1.1b

NSb

Non-ovarian endo

149

7.03

6.65

7.44

0.6b

<0.05b

6.62

6.48

6.84

0.7b

<0.05b

Ovarian endo

28

6.73

6.45

7.13

  

6.49

6.37

6.65

  

EmCa

14

8.61

8.06

9.24

1.9b

NS

6.28

6.14

7.29

0.6b

<0.05b

OvCa

15

9.25

8.36

10.04

5.7c

<0.05c

6.86

6.66

7.74

1.3c

<0.05c

  1. E=endometrium; EmCA=endometrial cancer; endo=endometriosis; OvCa=ovarian cancer; NS=not significant.
  2. aDunn's method.
  3. bCompared to endometrium specimens of healthy controls.
  4. cCompared to ovarian endometriomas.
Back to article page