Table 3 Correlations of (a) plasma total DNA, (b) serum methylated DNA, (c) CTC and (d) molecular markers

From: The presence of circulating total DNA and methylated genes is associated with circulating tumour cells in blood from breast cancer patients

 

Response

 

(a) Total DNA levels

Stable ( n =27)

Progressive ( n =46)

P -value

High

16

39

0.01

Low

11

7

 

(b) Methylated serum DNA

Stable ( n =26)

Progressive ( n =46)

 

Methylated

10

31

0.02

Unmethylated

16

15

 

(c) CTC

Stable ( n =26)

Progressive ( n =46)

 

Positive

5

22

0.02

Negative

21

24

 

(d) Molecular markers

Stable ( n =25)

Progressive ( n =46)

 

Negative

6

4

0.01

At least one marker positive

10

8

 

Two or more markers positive

7

18

 

Three markers positive

2

16

 
  1. CTC=circulating tumour cell.
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