Table 4 Aberrant methylation of genes by age

From: The presence of circulating total DNA and methylated genes is associated with circulating tumour cells in blood from breast cancer patients

 

Age (years)

 

Genes

<40 ( n =4)

40–49 ( n =14)

50–59 ( n =17)

⩾60 (n=44)

P -value

APC

0

3 (13%)

4 (17%)

16 (70%)

0.33

RASSF1A

1 (4%)

5 (18%)

4 (14%)

18 (64%)

0.61

ESR1

0

5 (31%)

3 (19%)

8 (50%)

0.35

At least one gene methylated

1 (2%)

6 (14%)

8 (19%)

27 (64%)

0.35

  1. Abbreviations: APC=adenomatous polyposis coli; ESR1=oestrogen receptor 1; RASSF1A=ras association domain family protein 1A.
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