Table 1 Odds ratios associated with truncating and missense CHEK2 mutations

From: Cancer risks in first-degree relatives of CHEK2 mutation carriers: effects of mutation type and cancer site in proband

Site of cancer

Truncating mutation OR (95%CI)

Missense mutations OR (95% CI)

Reference

Prostate

2.5 (1.6–3.7)

1.6 (1.3–2.1)

Cybulski et al (2004b)

Breast

3.3 (2.4–4.3)

1.6 (1.4–1.9)

Cybulski et al (2007a)

Colon

1.0 (0.5–1.8)

1.5 (1.2–2.0)

Cybulski et al (2007b)

  1. CI=confidence interval; OR=odds ratio.
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