Table 2 MTHFR combined genotypes classified according to expected activity of metylenetetrahydrofolate reductase

From: Predictors of survival and toxicity in patients on adjuvant therapy with 5-fluorouracil for colorectal cancer

Activity level

MTHFR C677T

MTHFR A1298C

N

High

C/C

A/A

10

Intermediate

C/C

C/C, A/C

78

 

T/T, C/T

A/A

 

Low

T/T, C/T

C/C, A/C

42

  1. Abbreviation: MTHFR=methylenetetrahydrofolate reductase.