Table 3 Ability to predict biochemical progression according to hnRNP K expression in the different cellular compartments

From: Heterogeneous nuclear ribonucleoprotein K: altered pattern of expression associated with diagnosis and prognosis of prostate cancer

hnRNP K expression

n

obs a

HR (95% CI)

P- value

Within the NM and the whole cell b

 ⩽0.60 and <10

16

2

1.0

0.1

 ⩽0.60 and ⩾10

14

6

3.96 (0.79–19.86)

0.1

 >0.60 and <10

7

3

5.03 (0.83–30.51)

0.08

 >0.60 and ⩾10

9

4

9.49 (1.61–55.82)

0.013

Within the NM and the cytoplasm

 ⩽0.60 and <4

12

2

1.0

0.1

 ⩽0.60 and ⩾4

18

6

2.41 (0.48–12.03)

0.3

 >0.60 and <4

7

3

3.89 (0.64–23.67)

0.1

 >0.60 and ⩾4

9

4

7.34 (1.25–43.13)

0.025

  1. aobs (observed)=number of patients with a biochemical progression.
  2. bhnRNP K expression level was determined within the NM by WB and in whole cell or in cytoplasm by IHC.
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