Table 1 Clinicopathological characteristics of responders and non-responders
IFNAR2-positive | IFNAR2-negative | |||
|---|---|---|---|---|
Responders ( n =10) | Non-responders ( n =10) | Non-responders ( n =10) | P -value | |
Age (year) | NS | |||
<60 | 6 | 7 | 5 | |
⩾60 | 4 | 3 | 5 | |
Sex | NS | |||
Male | 9 | 9 | 9 | |
Female | 1 | 1 | 1 | |
HBV infection | NS | |||
Present | 6 | 8 | 7 | |
Absent | 4 | 2 | 3 | |
HCV infection | 0.0180 | |||
Present | 7 | 1 | 3 | |
Absent | 3 | 9 | 7 | |
Child-pugh score | NS | |||
A | 7 | 7 | 5 | |
B, C | 3 | 3 | 5 | |
Liver cirrhosis | NS | |||
Present | 4 | 7 | 3 | |
Absent | 6 | 3 | 7 | |
α-fetoprotein (ng ml−1) | NS | |||
<300 | 5 | 1 | 3 | |
⩾300 | 5 | 9 | 7 | |
Tumour size (cm) | NS | |||
<5 | 2 | 3 | 2 | |
⩾5 | 8 | 7 | 8 | |
Histological grade | NS | |||
Moderately differentiated | 1 | 0 | 0 | |
Poorly differentiated | 9 | 8 | 9 | |
Undifferentiated | 0 | 2 | 1 | |
IFNAR2 expression | <0.0001 | |||
0 | 0 | 0 | 10 | |
1 | 8 | 10 | 0 | |
2 | 2 | 0 | 0 | |
