Figure 2
Effect of serum starvation on drug sensitivity in HSB2 cells. Cells were incubated in tissue culture medium containing either 10% or 1% fetal calf serum (FCS) for 7 days before measuring drug sensitivity. (A) Growth inhibitory effects of serum starvation after 7 days (arbitrary units, mean±s.e.m., n=9). (B) Cytotoxic effects of ARAC, DEX and MPRED (MTT assay, 4-day drug incubation). Data represent the mean percentage change in IC50 in serum-starved cells (1%) compared to control (10%) in 4–7 independent experiments.
