Table 3 Effect of over-expressing INHα on VEGF-A and VEGF-C expression

From: Elevated level of inhibin-α subunit is pro-tumourigenic and pro-metastatic and associated with extracapsular spread in advanced prostate cancer

 

LNCaP

PC3

 

EV clones

INH α clones

EV clones

INH α clones

VEGF-A

    

 Secreted protein (pg ml−1)

1751±33.48

1747±26.02

1794±40.31

1712±34.64

VEGF-C

    

 Secreted protein (pg ml−1)

5.86±2.66

7.82±2.13

3377±566.0

6892±531.6**

  1. Abbreviations: EV=empty vector; VEGF=vascular endothelial growth factor.
  2. Data from individual clones were pooled and presented above.
  3. **P=0.0011.