Table 5 Criteria for Dworak grades 1, 2 vs 3, 4, and their validities tested among the 60 patients

From: High Ki67, Bax, and thymidylate synthase expression well correlates with response to chemoradiation therapy in locally advanced rectal cancers: proposal of a logistic model for prediction

   

Pathological response

Validity

   

DG 3, 4

DG1, 2

DG 3, 4

DG 1, 2

Category

Definition ( P)

Definition (Π)

Responder ( n =29)

Non-responder ( n =31)

Se

Sp

Se

Sp

Responder

0.90⩽P

2.20⩽Π

13

0

44.8

100

  

Probable responder

0.50⩽P<0.90

0⩽Π<2.20

11

5

82.8

83.9

  

Unknown

0.40⩽P<0.50

−0.41<Π<0

1

1

    

Probable no-responder

0.20<P⩽0.40

−1.39<Π⩽−0.41

4

7

  

80.6

86.2

No-responder

P⩽0.20

Π⩽−1.39

0

18

  

58.1

100

  1. P, probability; DG, Dworak grade; Se, sensitivity; Sp, specificity; Π=loge (P/1−P).
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