Table 1 PI3K–AKT activating mutations and their coexistence in 97 endometrial cancers
From: The oncogenic mutation in the pleckstrin homology domain of AKT1 in endometrial carcinomas
n (%) | |
|---|---|
Wild-type | 24 (25) |
AKT1 mutation alone | 2 (2) |
K-Ras mutation alone | 4 (4) |
PIK3CA mutation alone | 6 (6) |
PTEN mutation alone | 30 (31) |
Double mutations of K-Ras and PIK3CA (w/o PTEN mutation) | 2 (2) |
Double mutations of K-Ras and PTEN (w/o PIK3CA mutation) | 3 (3) |
Double mutations of PIK3CA and PTEN (w/o K-Ras mutation) | 18 (19) |
Triple mutations of K-Ras, PIK3CA and PTEN | 8 (8) |
