Table 2 Genotype distributions of SNPs, selected by univariate analysis of PFS, OS and toxicity
SNP | Wild type, N (%) | Heterozygotes, N (%) | Homozygote mutants, N (%) | Total, N |
---|---|---|---|---|
ATM rs1801516 | 63 (69.2) | 24 (26.4) | 4 (4.4) | 91 |
ERCC5 rs1047768 | 28 (30.8) | 46 (50.5) | 17 (18.7) | 91 |
GADD45A rs532446 | 49 (55.1) | 31 (34.8) | 9 (10.1) | 89 |
LIG4 rs1805388 | 62 (68.1) | 27 (29.7) | 2 (2.2) | 91 |
BARD1 rs2070093 | 62 (68.1) | 25 (27.5) | 4 (4.4) | 91 |
ERCC2 rs238406 | 27 (30.0) | 46 (51.1) | 17 (18.9) | 90 |