Figure 2

PARP activity in the cell line panel. (A) PAR formation detected by immunoblot assay. (B) Semiquantitative analysis of the results of replicate experiments of the kind shown in A: Columns, mean of samples analysed in triplicate in three separate experiments; bars, s.d. (C) PARP activity (expressed as log10) in individuals with 2444 TT, TC, and CC genotype, respectively. P-value calculated by Student's t-test (T/T vs C/C).