Figure 9 | British Journal of Cancer

Figure 9

From: Dexrazoxane-afforded protection against chronic anthracycline cardiotoxicity in vivo: effective rescue of cardiomyocytes from apoptotic cell death

Figure 9

(A) Horizontal Hierarchical Tree Plot. The analysis comprised LV functional parameters (FS and dP/dtmax), the plasma levels of cardiac troponins T and I, markers of apoptosis (TUNEL positivity and activities of caspases) and lipoperoxidation (nine variables) in all experimental groups. The analysis resulted in two main clusters. The first cluster covers exclusively the individuals from the control (C) and DEX co-treated group (DD), whereas the second cluster contains only the animals from the daunorubicin group (D), where almost all animals appeared in one cluster. (B) Principal Component Analysis (PCA) scatterplots. This analysis of the same variables also revealed two distinctly separated clusters comprising the DEX+DAU and control groups in the first, with all animals from the DAU group in the second cluster. Treatment groups: control (), DAU () and DEX+DAU (□).

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