Figure 1

Schematic representation of five Dicer mRNA variants and their corresponding proteins according to AceView (http://www.ncbi.nlm.nih.gov/ieb/research/acembly/), transcription from the Dicer gene produces 14 mRNAs, 11 alternatively spliced variants and 3 full-length forms. The three full-length mRNA variants a, b, and c, the corresponding full-length protein (218 kDa) and the two alternatively spliced variants, d and e, and their corresponding proteins (113 and 93 kDa, respectively) are shown. Coloured areas represent the coding region and black bars represent 5′UTR and 3′UTR. Domain structures are represented on proteins.