Table 1 Quantitative RT–PCR analysis of Dicer expression in breast cancer cell lines and correlation with clinicopathological characteristics
Biological and clinical | Cases | Measures | Dicer | |
|---|---|---|---|---|
characteristics | n=23 | 111 | Mean CI | P -value |
Cell phenotype | ||||
Epithelial | 11 | 55 | 4.056 (3.230–5.093) | 0.0002 |
Mesenchymal | 7 | 35 | 1.763 (1.363–2.282) | |
Tumour stage | ||||
Immortalized cell | 3 | 15 | 2.198 (1.577–3.064) | <0.0001 |
Intra-ductal carcinoma (DCIS) | 4 | 20 | 4.107 (3.445–4.895) | |
Invasive ductal carcinoma (IDC) | 12 | 60 | 1.524 (NA) | |
Metastases | 1 | 5 | 1.369 (1.045–1.794) | |