Figure 1

The downregulated miR-143 expression in both primary colorectal cancer tissues and colon cancer cell lines. (A) The relative miR-143 expression between tumour tissues and their paired adjacent colonic normal tissues from 30 CRC patients using real-time qPCR. Expression of miR-143 (Log₁₀ scale at Y axis) was normalised to U6. Statistical difference was analysed using Wilcoxon's test, P<0.0001. (B) The relative miR-143 expression in colon cancer cell lines was much lower than that of the three non-cancerous colonic tissues (N1, N2, and N3).