Figure 6
From: Peripheral neural cell sensitivity to mTHPC-mediated photodynamic therapy in a 3D in vitro model
Neurons survive mTHPC-mediated PDT and produce new neurite outgrowth. After treatment with mTHPC-mediated PDT in 3D culture, neurons were grown in 2D in the presence of untreated satellite glia for 2 days. A similar number of neuronal cell bodies had neurites associated with them in the 3–4 μg ml–1 mTHPC-mediated PDT samples as in the controls (A). There was a similar level of neurite length detected in controls and treated neurons, except for the samples that had received 10 μg ml–1 mTHPC-mediated PDT, which showed a significant reduction in neurite length (*P<0.05) (B).
