Table 2 Multivariate hazard ratios according to time period for each cancer site

From: Idiopathic venous thromboembolic disease is associated with a poorer prognosis from subsequent malignancy

 

Multivariate hazard ratio according to time period from diagnosis of VTE to diagnosis of malignancy

Cancer site

Control group

0–6 months

>6–12 months

>1–2 years

>2–5 years

Oesophagus

1.00

2.45 (1.78–3.38)a

2.50 (1.25–5.01)b

0.73 (0.44–1.21)

0.84 (0.54–1.31)

Stomach

1.00

2.35 (1.98–2.79)a

1.61 (1.02–2.52)b

1.61 (1.04–2.50)b

0.87 (0.61–1.23)

Colon

1.00

1.95 (1.73–2.21)a

1.23 (0.83–1.84)

1.41 (1.01–1.98)b

1.16 (0.91–1.47)

Rectum

1.00

2.72 (2.12–3.49)a

1.62 (0.73–3.62)

2.60 (1.17–5.80)b

1.08 (0.74–1.58)

Pancreas

1.00

3.23 (2.77–3.77)a

0.97 (0.46–2.04)

0.70 (0.41–1.19)

1.36 (0.85–2.20)

Lung

1.00

1.93 (1.77–2.12)a

1.05 (0.82–1.35)

1.08 (0.88–1.32)

0.88 (0.75–1.04)

Breast

1.00

2.61 (2.09–3.27)a

0.86 (0.50–1.49)

1.14 (0.78–1.68)

1.18 (0.90–1.55)

Cervix uteri

1.00

4.84 (3.22–7.29)a

4.03 (1.0–16.22)b

1.45 (0.54–3.89)

1.44 (0.75–2.77)

Corpus uteri

1.00

3.87 (2.62–5.72)a

1.38 (0.44–4.33)

0.43 (0.06–3.06)

2.51 (0.94–6.73)

Ovary

1.00

2.34 (1.99–2.75)a

1.30 (0.72–2.36)

1.22 (0.55–2.72)

1.17 (0.70–1.95)

Prostate

1.00

2.07 (1.75–2.45)a

1.14 (0.78–1.66)

0.71 (0.45–1.09)

1.46 (1.17–1.83)a

Kidney

1.00

2.00 (1.55–2.57)a

0.94 (0.47–1.89)

1.13 (0.42–3.03)

2.07 (1.32–3.26)a

Bladder

1.00

2.24 (1.74–2.88)a

1.40 (0.67–2.93)

1.39 (0.81–2.40)

1.12 (0.82–1.52)

Non-Hodgkins lymphoma

1.00

2.09 (1.72–2.54)a

1.36 (0.70–2.61)

1.24 (0.62–2.48)

1.07 (0.65–1.75)

Lymphoid leukaemia

1.00

1.61 (1.12–2.29)b

1.20 (0.45–3.20)

1.04 (0.54–2.01)

0.89 (0.49–1.62)

All malignanciesc

1.00

2.48 (2.38–2.58) P<0.001

1.21 (1.07–1.37) P=0.002

1.26 (1.13–1.40) P<0.001

1.07 (0.99–1.15) P=0.079

  1. ICD=International Classification of Diseases; VTE=venous thromboembolism.
  2. Results quoted are hazard ratios with 95% lower and upper confidence intervals in brackets.
  3. aIndicates a P-value of <0.001.
  4. bIndicates a P-value of ⩽0.05.
  5. cAll malignancies within the range ICD 10 C00-C96, excluding non-melanomatous skin cancer.
Back to article page