Figure 3 | British Journal of Cancer

Figure 3

From: Combination of cetuximab with chemoradiation, trastuzumab or MAPK inhibitors: mechanisms of sensitisation of cervical cancer cells

Figure 3

Western blotting analysis of basal and phosphorylated signalling pathways before and after cetuximab (100 μg ml−1) treatment. (A) Basal levels of total and phosphorylated EGFR, HER2/neu and downstream signalling proteins. (B, C and D) Effects of cetuximab on EGF-induced activation of EGFR (Tyr 845, 992, 1045 and 1068), HER-2/neu, AKT and ERK1/2 of A431, Caski and C33A cells, respectively, detected by western blotting.

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