Table 4 Summary of multivariate Cox's regression analyses of securin immunoexpression performed in invasive breast carcinomas and in subgroups divided according to invasive ductal histology (IDC) and Ki-67 immunopositivity (low, <10%; high, 10%)

From: Securin promotes the identification of favourable outcome in invasive breast cancer

 

n

P

HR

95% CI

All

257

0.028

2.3

1.1–5.0

 Ki-67<10%

106

0.031

5.1

1.2–22.7

 Ki-6710%

134

0.617

  

IDC

211

0.051

  

 Ki-67<10%

84

0.024

13.1

1.4–121.3

 Ki-6710%

118

0.719

  
  1. The results are based on the optimal cut-point determined at 1.5% of securin immunopositivity, derived from analysis of breast cancer-specific survival of the patient data. Axillary lymph node status, patient's age and tumour size at the time of diagnosis were used as covariates in multivariate analyses.