Table 4 Multivariable analysis of clinical and molecular factors and PFS

From: Molecular markers of response and toxicity to FOLFOX chemotherapy in metastatic colorectal cancer

Variable

Hazard ratio

95% CI

P

Number of organs involved

 1

1.00

  

 >1

1.62

1.21–2.15

0.001

Absolute neutrophil count at baseline

 < ULNa

1.00

  

 ⩾ULN

1.12

1.03–1.21

0.009

ERCC1-118

 CC

1.00

  

 CT and TT

2.16

0.94–4.97

0.07

  1. aThe upper limit of normal (ULN) for neutrophils was 7 × 109 per litre.
Back to article page