Table 6 Incidence of diarrhoea according to MTHFR C677T genotype

From: Molecular markers of response and toxicity to FOLFOX chemotherapy in metastatic colorectal cancer

Genotype

Grades 0–2, n (%)

Grades 3–4, n (%)

P

MTHFR 677

 CC

40 (38)

3 (27)

 

 CT

51 (49)

3 (27)

 

 TT

14 (13)

5 (45)

0.02a

  1. aFisher's exact test (TT vs CT/CT genotype).