Table 2 Grade 3 and 4 adverse events in the gemcitabine group (n=57)

From: A randomised phase III trial comparing gemcitabine with surgery-only in patients with resected pancreatic cancer: Japanese Study Group of Adjuvant Therapy for Pancreatic Cancer

 

Gemcitabine

 

Grade 3 a

Grade 4 a

Adverse event

No.

%

No.

%

Heamatological

 Leukopenia

13

23

1

2

 Neutropenia

32

56

8

14

 Anaemia

2

4

0

0

 Thrombocytopenia

1

2

0

0

Non-heamatological

 Diarrhoea

1

2

0

0

 Fever

1

2

0

0

 Nausea

0

0

1

2

 Anorexia

1

2

1

2

 Fatigue

1

2

0

0

 AST

3

5

0

0

 ALT

4

7

0

0

 Abscess

0

0

1

2

  1. Abbreviations: ALT=alanine aminotransferase; AST=aspartate aminotransferase.
  2. aNCI Common Toxicity Criteria, version 2.0.