Table 2 Maximum toxicity per patient according to the NCI-CTC grade (n=53)

From: Capecitabine in combination with irinotecan (XELIRI), administered as a 2-weekly schedule, as first-line chemotherapy for patients with metastatic colorectal cancer: a phase II study of the Spanish GOTI group

 

All grades

Grade 3

 

n

%

n

%

Haematological events

 Anaemia

23

43

—

—

 Leucopenia

4

8

—

—

 Neutropenia

12

23

3

6

 Thrombopenia

3

6

1

2

Non-haematological events

 Fever

8

15

—

—

 Alopecia

14

26

2

4

 Nausea

30

57

4

8

 Vomiting

24

45

2

4

 Diarrhoea

27

51

8

15

 Epigastralgia

8

15

1

2

 Asthenia

30

57

7

13

 Headache

3

6

—

—

 Hand–foot syndrome

7

13

—

—

 Mucositis

11

21

—

—

 Liver

2

4

—

—

 Renal

2

4

1

2

 Skin

3

6

—

—

 Anorexia

11

21

1

2

  1. Abbreviation: NCI-CTC=National Cancer Institute-Common Toxicity Criteria.
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