Table 3 Independent predictors for relapse-free survival in 256 patients with colon cancer TNM stages II and III, according to Cox regression model

From: Expression of EZH2 and Ki-67 in colorectal cancer and associations with treatment response and prognosis

Variable

Hazard ratio (95% CI)

P -value

TNM stage

<0.0001

 Stage II

1

 

 Stage III

4.00 (2.50–6.39)

 

Ki-67 staining

0.014

 <40%

1

 

 ⩾40%

0.55 (0.34–0.89)

 

Tumour grade

0.022

 High or moderate differentiation

1

 

 Poor differentiation

1.80 (1.09–2.98)

 

Randomisation group

0.31

 No adjuvant therapy

1

 

 Adjuvant chemotherapy

0.80 (0.51–1.24)

 

Tumour localisation

0.27

 Proximal colon

1

 

 Distal colon

1.28 (0.82–1.99)

 
  1. Abbreviations: CI=confidence interval; TNM=tumor–node–metastasis.
  2. Cox analysis (enter) was based on 256 out of 284 patients with colon cancer TNM stages II and III, and 28 cases had missing data for one variable.
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