Figure 1

Kaplan–Meier estimates for TTP in the combined studies. TTP is stratified by HER2 IHC Score. Median IHC 0/1=8 weeks; IHC 2+=12 weeks; IHC 3+=16 weeks. (log rank P=0.0083); 23 out of 26 HER2 IHC2+ tumours were FISH positive, 3 out of 26 tumours were non-evaluable by FISH.