Figure 5
From: Gene silencing of HPV16 E6/E7 induced by promoter-targeting siRNA in SiHa cells

Cellular apoptosis and senescence in SiHa cells treated by promoter–siRNA. (A). Apoptosis of SiHa cells treated by siRNA. In the flow cytometry chart, the x-axes represent the fluorescence intention of annexin-V–FITC, and y-axes show the fluorescence intensity of propidium iodide and the dot in the quadrant represents the cell number. The right down quadrant shows apoptosis data. (B) Senescence of SiHa cells treated by siRNA (200 × ). Cells that showed intense green staining reflected high levels of SAβ-gal activity. Further green staining appeared in cells treated with promoter-targeting siRNA. The colour version of this figure is available online.