Figure 3 | British Journal of Cancer

Figure 3

From: Humanised IgG1 antibody variants targeting membrane-bound carcinoembryonic antigen by antibody-dependent cellular cytotoxicity and phagocytosis

Figure 3

Effect of FcγR blocking on unmodified humanised PR1A3-induced ADCC, using anti-CD16, 32 and 64 Fab2 or IgG. SKCO-1 was used as the target and NK cells as the effectors (effector : target ratio=8 : 1). The P-values are for the significance of the differences between the result using hIgG1PR1A3 and no blocking antibody, based on t-tests.

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