Table 4 Results of multivariate Cox regression analysis of disease-free survival with stepwise selection

From: Change in the hormone receptor status following administration of neoadjuvant chemotherapy and its impact on the long-term outcome in patients with primary breast cancer

Variables

Hazard ratio (95% CI)

P -value

Group

 A

1

 

 B

1.16 (0.61, 2.19)

0.652

 C

6.88 (3.00, 15.80)

<0.001

 D

1.63 (1.01, 2.63)

0.045

Clinical stage

 IIA/IIB/IIIA

1

 

 IIIB/IIIC

1.56 (1.00, 2.42)

0.049

HER2

 Negative

1

 

 Positive

2.00 (1.30, 3.09)

0.002

Clinical response

 SD/PD

1

 

 PR/CR

0.56 (0.34, 0.92)

0.021

Number of lymph node metastases

 0

1

 

 1–3

2.09 (1.14, 3.83)

0.017

 >4

6.49 (3.71, 11.37)

<0.001

  1. Abbreviations: CI=confidence interval; CR=complete response; PR=partial response; SD=stable disease; PD=progression disease.
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