Table 1 Impact of adjuvant therapies on 5-year breast cancer mortality

From: The size of the prize for earlier diagnosis of cancer in England

 

5-year breast cancer mortality

 

Without (%)

With (%)

Difference (%)

Radiotherapy

 Breast-conserving surgery (node negative)

8.9

8.0

0.9

 Breast-conserving surgery (node positive)

24.3

20.9

3.4

 Mastectomy+axillary clearance (no)

12.5

11.3

1.2

 Mastectomy+axillary clearance (n+)

34.0

32.1

1.9

Chemotherapy

 Polychemotherapy (age <50 years)

20.4

15.7

4.7

 Polychemotherapy (age 50–69 years)

21.3

18.7

1.6

Hormonal therapy

 Tamoxifen (about 5 years) in ER-positive or ER-unknown disease

11.9

8.3

3.6

 Ovarian ablation or suppression in ER-positive or ER-unknown disease

18.4

16.6

1.8

  1. Abbreviations: ER=estrogen receptor.
  2. Note: Figures taken from EBCTCG (2005a, 2005b).