Table 2 Cox proportional hazards analysis for treatment effects on survival

From: Tumour-targeted delivery of TRAIL using Salmonella typhimurium enhances breast cancer survival in mice

Treatment

n

Median survival ( d)

Hazard ratios

Hazard ratios, stratified by radiation treatment

PBS

11

14.0 (11.7–16.3)

—

—

PBS+2 Gy

11

14.0 (9.7–18.3)

0.97 (0.42–2.24)

—

VNP pRZ

8

16.0 (12.3–19.7)

0.63 (0.24–1.65)

0.58 (0.22–1.55)

VNP pRZ+2 Gy

6

18.0 (11.2–24.8)

0.53 (0.18–1.54)

0.58 (0.20–1.74)

VNP pRT

11

22.0 (14.6–29.4)

0.41 (0.16–1.04)

0.38 (0.15–1.00)

VNP pRT+2 Gy

8

26.0 (14.9–37.1)

0.21 (0.07–0.63)*

0.24 (0.08–0.75)*

  1. Median survival times and hazard ratios are listed with their 95% confidence intervals in parentheses.
  2. *Significance is indicated as P<0.05.
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